But in substances, wherein a real essence, distinct from the nominal, is supposed to constitute, determine, and bound the species, the extent of the general word is very uncertain; because, not knowing this real essence, we cannot know what is, or what is not of that species; and, consequently, what may or may not with certainty be affirmed of it. And thus, speaking of a man, or gold, or any other species of natural substances, as supposed constituted by a precise and real essence which nature regularly imparts to every individual of that kind, whereby it is made to be of that species, we cannot be certain of the truth of any affirmation or negation made of it. For man or gold, taken in this sense, and used for species of things constituted by real essences, different from the complex idea in the mind of the speaker, stand for we know not what; and the extent of these species, with such boundaries, are so unknown and undetermined, that it is impossible with any certainty to affirm, that all men are rational, or that all gold is yellow. But where the nominal essence is kept to, as the boundary of each species, and men extend the application of any general term no further than to the particular things in which the complex idea it stands for is to be found, there they are in no danger to mistake the bounds of each species, nor can be in doubt, on this account, whether any proposition be true or not. I have chosen to explain this uncertainty of propositions in this scholastic way, and have made use of the terms of essences, and species, on purpose to show the absurdity and inconvenience there is to think of them as of any other sort of realities, than barely abstract ideas with names to them. To suppose that the species of things are anything but the sorting of them under general names, according as they agree to several abstract ideas of which we make those names the signs, is to confound truth, and introduce uncertainty into all general propositions that can be made about them. Though therefore these things might, to people not possessed with scholastic learning, be treated of in a better and clearer way; yet those wrong notions of essences or species having got root in most people's minds who have received any tincture from the learning which has prevailed in this part of the world, are to be discovered and removed, to make way for that use of words which should convey certainty with it.
5. This more particularly concerns substances. The names of substances, then, whenever made to stand for species which are supposed to be constituted by real essences which we know not, are not capable to convey certainty to the understanding. Of the truth of general propositions made up of such terms we cannot be sure. The reason whereof is plain: for how can we be sure that this or that quality is in gold, when we know not what is or is not gold? Since in this way of speaking, nothing is gold but what partakes of an essence, which we, not knowing, cannot know where it is or is not, and so cannot be sure that any parcel of matter in the world is or is not in this sense gold; being incurably ignorant whether it has or has not that which makes anything to be called gold; i.e. that real essence of gold whereof we have no idea at all. This being as impossible for us to know as it is for a blind man to tell in what flower the colour of a pansy is or is not to be found, whilst he has no idea of the colour of a pansy at an. Or if we could (which is impossible) certainly know where a real essence, which we know not, is, v.g. in what parcels of matter the real essence of gold is, yet could we not be sure that this or that quality could with truth be affirmed of gold; since it is impossible for us to know that this or that quality or idea has a necessary connexion with a real essence of which we have no idea at all, whatever species that supposed real essence may be imagined to constitute.
6. The truth of few universal propositions concerning substances is to be known. On the other side, the names of substances, when made use of as they should be, for the ideas men have in their minds, though they carry a clear and determinate signification with them, will not yet serve us to make many universal propositions of whose truth we can be certain. Not because in this use of them we are uncertain what things are signified by them, but because the complex ideas they stand for are such combinations of simple ones as carry not with them any discoverable connexion or repugnancy, but with a very few other ideas.
7. Because necessary co-existence of simple ideas in substances can in few cases be known. The complex ideas that our names of the species of substances properly stand for, are collections of such qualities as have been observed to co-exist in an unknown substratum, which we call substance; but what other qualities necessarily co-exist with such combinations, we cannot certainly know, unless we can discover their natural dependence; which, in their primary qualities, we can go but a very little way in; and in all their secondary qualities we can discover no connexion at all: for the reasons mentioned, chap. iii. Viz. 1. Because we know not the real constitutions of substances, on which each secondary quality particularly depends. 2. Did we know that, it would serve us only for experimental (not universal) knowledge; and reach with certainty no further than that bare instance: because our understandings can discover no conceivable connexion between any secondary quality and any modification whatsoever of any of the primary ones. And therefore there are very few general propositions to be made concerning substances, which can carry with them undoubted certainty.